abstract：:Two patients presented with the unusual condition of multiple warty dyskeratomas on the scalp. Biopsies of affected skin stained positive with human keratin monoclonal antibodies HKN-6 and -7, specific for cortex and inner root sheath of normal human hair, respectively. Multiple warty dyskeratomas are a rare occurrenc...

journal_title：Clinical and experimental dermatology

authors： Griffiths TW,Hashimoto K,Sharata HH,Ellis CN

更新日期：1997-07-01 00:00:00

abstract：:Drug reactions are common in HIV-1 disease, with the incidence having been reported to increase with increasing stage and with CD4+ T-cell counts below 200/microliters. However, there have been numerous reports of patients in which rechallenge, dosing changes or continued therapy have resulted in no recurrence or else...

journal_title：Clinical and experimental dermatology

authors： Smith KJ,Skelton HG,Yeager J,Ledsky R,Ng TH,Wagner KF

更新日期：1997-05-01 00:00:00

abstract：:Dermatomyositis (DM) in a inflammatory disorder of skeletal muscle and skin closely related to other connective tissue diseases; however, to date, no conclusive immunofluorescence (IMF) data are available for the disorder. The aim of this study was therefore to analyse retrospectively the clinical, histological and di...

journal_title：Clinical and experimental dermatology

authors： Jones SA,Black MM

更新日期：1997-03-01 00:00:00

abstract：:In primary localized cutaneous amyloid, deposition of amyloid is confined to the skin without the involvement of any internal organs. Amyloid deposition in the skin is often scanty, and electron microscopy may be needed to confirm the presence of the typical amyloid fibrils. There have been several case reports of cut...

journal_title：Clinical and experimental dermatology

authors： Macsween RM,Saihan EM

更新日期：1997-01-01 00:00:00

abstract：:We report the case of a 46-year-old Indian woman who developed a hyperimmune response to a typhoid booster injection in association with the development of pemphigus vulgaris. To our knowledge, this association has not previously been reported. ...

journal_title：Clinical and experimental dermatology

authors： Bellaney GJ,Rycroft RJ

更新日期：1996-11-01 00:00:00

abstract：:Histology sections from 61 cases of squamous cell carcinoma (SCC) of the vulva presenting after 1988 were reviewed for evidence of associated epithelial abnormality. Of the 50 patients with epithelium adjacent to the tumour, 24 had histological evidence of lichen sclerosus (LS), 20 of severe vulvar intraepithelial neo...

journal_title：Clinical and experimental dermatology

authors： Zaki I,Dalziel KL,Solomonsz FA,Stevens A

更新日期：1996-09-01 00:00:00

abstract：:Mycosis fungoides (MF) is the most common cutaneous T-cell lymphoma. We report a case in which identical T-cell clones were identified in both patch and tumour stage lesions and in which the tumorous deposits, containing CD30-positive cells, regressed spontaneously. We discuss the differential diagnosis of the tumorou...

journal_title：Clinical and experimental dermatology

authors： Woodrow SL,Basarab T,Russell Jones R

更新日期：1996-09-01 00:00:00

abstract：:Porphyria cutanea tarda (PCT) is believed to be associated with reduced hepatic uroporphyrinogen decarboxylase activity and risk factors such as alcohol abuse and medication with oral contraceptives and certain other drugs. Recently it has been suggested that hepatitis C virus (HCV) infection may also be associated wi...

journal_title：Clinical and experimental dermatology

authors： Hussain I,Hepburn NC,Jones A,O'Rourke K,Hayes PC

更新日期：1996-07-01 00:00:00

abstract：:Cutaneous amyloidosis and multiple endocrine neoplasia 2A (MEN 2A) have been previously reported in several families. A genetic linkage of both disorders has recently been described. Notalgia paraesthetica has been suggested to be involved in the aetiology of amyloidosis in such patients. We report such an association...

journal_title：Clinical and experimental dermatology

authors： de Argila D,Ortiz-Romero PL,Ortiz-Frutos J,Rodriguez-Peralto JL,Iglesias L

更新日期：1996-07-01 00:00:00

abstract：:We describe the case of a 68-year-old woman who presented with asymptomatic skin nodules and symptoms of anaemia, and was found to have acute megakaryoblastic leukaemia with fibrosis, a condition now believed to correspond to the former diagnosis of acute myelofibrosis. There is only one previous report of skin lesion...

journal_title：Clinical and experimental dermatology

authors： Macfarlane AW,Parry DH,Caslin AW,Hughes M

更新日期：1996-05-01 00:00:00

abstract：:An essential property of the immune system is its ability to generate diverse antibody and T-cell mediated responses to virtually any potential foreign particle. The basic molecular mechanisms responsible for producing this extensive diversity have now been elucidated. Each T cell expresses a unique membrane bound T-c...

journal_title：Clinical and experimental dermatology

authors： Whittaker S

更新日期：1996-03-01 00:00:00

abstract：:A 15-year-old boy with Kaposi's varicelliform eruption complicating healing second degree burns is reported. Clinically, umbilicated vesicles and pustules evolving to extensive erosions appeared over previously burned areas, sparing normal skin. Rapid diagnosis was made on the basis of the presence of multinucleate gi...

journal_title：Clinical and experimental dermatology

authors： Bartralot R,García-Patos V,Rodríguez-Cano L,Castells A

更新日期：1996-03-01 00:00:00

abstract：:Tumoral calcinosis is an uncommon ectopic calcification syndrome characterized clinically by the presence of irregular, painless, periarticular soft tissue calcifying masses, and pathologically by fibrous-walled cystic spaces containing structureless calcific debris and associated with a variable inflammatory reaction...

journal_title：Clinical and experimental dermatology

authors： Harwood CA,Cook MG,Mortimer PS

更新日期：1996-03-01 00:00:00

abstract：:This prospective study was undertaken to determine whether the 2-mm punch biopsy technique yields specimens of sufficient size and quality to allow a reliable histological diagnosis to be made. A histopathological comparison was made between tissue obtained from a 2-mm punch biopsy and a standard ellipse biopsy taken ...

journal_title：Clinical and experimental dermatology

authors： Todd P,Garioch JJ,Humphreys S,Seywright M,Thomson J,du Vivier AW

更新日期：1996-01-01 00:00:00

abstract：:A female patient is presented who consistently developed lesions of disseminated superficial porokeratosis (DSP) whilst on holiday abroad. The lesions resolved completely within 4-6 weeks of return to the UK. Induction of the lesions by exposure to artificial sources of UVA and UVB was unsuccessful. Disseminated super...

journal_title：Clinical and experimental dermatology

authors： Ibbotson SH

更新日期：1996-01-01 00:00:00

abstract：:We report the case of a 26-year-old man with haemophilia B and human immunodeficiency virus infection (HIV) who presented with a short history of multiple dermatofibromas. He also had troublesome psoriasis for which he was receiving acitretin with UVB therapy and had recently discontinued low-dose daily prednisolone f...

journal_title：Clinical and experimental dermatology

authors： Armstrong DK,Irvine A,Walsh MY,Mayne EE,Burrows D

更新日期：1995-11-01 00:00:00

abstract：:Partial unilateral lentiginosis is a rare disorder of cutaneous pigmentation characterized by the presence of multiple lesions of simple lentigo involving, wholly or partially, one half of the body. We report seven cases of this condition. ...

journal_title：Clinical and experimental dermatology

authors： Piqué E,Aguilar A,Fariña MC,Gallego MA,Escalonilla P,Requena L

更新日期：1995-07-01 00:00:00

abstract：:Azathioprine is used in a variety of dermatological conditions. However, because of its side-effect profile, azathioprine is limited for use in patients with severe disease. An unpredictable, rare and potentially fatal side-effect of azathioprine is the development of a hypersensitivity reaction, often consisting of f...

journal_title：Clinical and experimental dermatology

authors： Knowles SR,Gupta AK,Shear NH,Sauder D

更新日期：1995-07-01 00:00:00

abstract：:Nodular cystic fat necrosis shows a distinctive spectrum of clinical and histological features. Most of the lesions are mobile subcutaneous nodules in regions vulnerable to trauma, such as the elbows, knees, and shins. There have been no reports of an association with other conditions. The histology is characterized b...

journal_title：Clinical and experimental dermatology

authors： Ahn SK,Lee BJ,Lee SH,Lee WS

更新日期：1995-05-01 00:00:00

abstract：:Contact allergy to various essential oils used in aromatherapy was demonstrated on patch testing in a 53-year-old patient suffering from relapsing eczema resistant to therapy on various uncovered parts of the skin, in particular the scalp, neck and hands. Sensitization was due to previous exposure to lavender, jasmine...

journal_title：Clinical and experimental dermatology

authors： Schaller M,Korting HC

更新日期：1995-03-01 00:00:00

abstract：:We report a patient with chronic urticaria which was closely associated with elevated levels of thyroxine. The urticaria responded poorly to antihistamines and only partially to systemic steroids, but resolved consistently when the thyroxine level was reduced to normal. The mechanism for the association may involve mo...

journal_title：Clinical and experimental dermatology

authors： Henderson CA,Highet AS

更新日期：1995-03-01 00:00:00

abstract：:We report the occurrence of severe symptomatic bronchoconstriction in an atopic asthmatic subject following the application of coal tar bandages. Investigations showed that this was likely to have been caused by inhalation of coal tar vapour. We suggest that coal tar preparations should be used with caution in asthmat...

journal_title：Clinical and experimental dermatology

authors： Ibbotson SH,Stenton SC,Simpson NB

更新日期：1995-01-01 00:00:00

abstract：:We performed an immunohistochemical study with 11 antikeratin antibodies using the newly developed AMeX (acetone-methylbenzoate-xylene) tissue processing method. Specimens processed with this method showed almost as good preservation and morphological detail as routinely processed, formalin-fixed and paraffin-embedded...

journal_title：Clinical and experimental dermatology

authors： Ansai SI,Koseki S,Hozumi Y,Kondo S

更新日期：1994-11-01 00:00:00

abstract：:The disaccharide content of the chondroitinase-digestible glycosaminoglycans (GAGs) extracted from 6-mm skin punch biopsies from the atrophic and sclerotic skin of two patients with Werner's syndrome (WS) were determined using high-performance liquid chromatography after 1-phenyl-3-methyl-5-pyrazolone labelling. The t...

journal_title：Clinical and experimental dermatology

authors： Higuchi T,Ishikawa O,Hayashi H,Ohnishi K,Miyachi Y

更新日期：1994-11-01 00:00:00

abstract：:A family with pachyonychia congenita in which affected individuals showed nail involvement only is described. Pachyonychia congenita is a rare hereditary disorder inherited in an autosomal dominant manner. Various classifications of pachyonychia congenita have been suggested but none indicates nail involvement as a so...

journal_title：Clinical and experimental dermatology

authors： Pryce DW,Verbov JL

更新日期：1994-11-01 00:00:00

abstract：:Knowledge of the physiology of wound healing, in particular the recovery of the dermal and epidermal compartments and the co-ordination of these processes by the cytokine network, is of great importance to rational wound management. The individual components of the wound healing process have been studied using various...

journal_title：Clinical and experimental dermatology

authors： Van de Kerkhof PC,Van Bergen B,Spruijt K,Kuiper JP

更新日期：1994-09-01 00:00:00

abstract：:We present a case of neonatal lupus erythematosus (NLE) in a black infant presenting with symmetrical depigmented macules on the face resembling vitiligo. NLE is a rare condition affecting newborn infants of mothers who have connective tissue disease, with or without autoantibodies to extractable nuclear antigens Ro (...

journal_title：Clinical and experimental dermatology

authors： Jenkins RE,Kurwa AR,Atherton DJ,Black MM

更新日期：1994-09-01 00:00:00

abstract：:We describe the case of a woman from a small town in the south of Spain, with consanguineous parents, who presented with the complete syndrome. The main clinicopathological characteristics are discussed. ...

journal_title：Clinical and experimental dermatology

authors： Bañuls J,Betlloch I,Botella R,Sevila A,Morell A,Román P

更新日期：1994-09-01 00:00:00

abstract：:Despite scarring being a recognized sequel of acne, the actual extent and incidence of residual scarring remains unknown. One hundred and eighty-five acne patients were included in this study (101 females, 84 males). Patients were selected from acne clinics and their acne scarring was examined. The scarring was quanti...

journal_title：Clinical and experimental dermatology

authors： Layton AM,Henderson CA,Cunliffe WJ

更新日期：1994-07-01 00:00:00

abstract：:The case of a 40-year-old man with delusions of parasitosis as the presentation of a monodelusional psychosis is reported. In spite of treatment with pimozide and depot neuroleptics the patient committed suicide. Since the introduction of pimozide, this drug has come to be regarded as the specific treatment for this d...

journal_title：Clinical and experimental dermatology

authors： Monk BE,Rao YJ

更新日期：1994-07-01 00:00:00

abstract：:Three cases of chondrodermatitis nodularis helicis (CDNH) in patients with the limited form of systemic sclerosis are described. Two of the three cases were noted during regular follow-up visits and the third case was found as part of a survey of the 21 other patients with systemic sclerosis routinely seen in the depa...

journal_title：Clinical and experimental dermatology

authors： Bottomley WW,Goodfield MD

更新日期：1994-05-01 00:00:00

abstract：:Clear cell acanthoma (CCA) is a benign epidermal tumour with distinctive and uniform clinical and histological features. Although solitary lesions are the rule, some cases of multiple CCA, rarely with more than 10 lesions, have been previously reported. Only 22 cases of multiple CCA have been described in the English ...

journal_title：Clinical and experimental dermatology

authors： Innocenzi D,Barduagni F,Cerio R,Wolter M

更新日期：1994-05-01 00:00:00

abstract：:The effect of dietary supplementation with a combination of n-3 (marine oil) and n-6 (evening primrose oil) essential fatty acids in the treatment of chronic stable plaque psoriasis was observed. Thirty-seven patients in a double-blind parallel trial were studied. There was no significant improvement in clinical sever...

journal_title：Clinical and experimental dermatology

authors： Oliwiecki S,Burton JL

更新日期：1994-03-01 00:00:00

abstract：:Naevus comedonicus is a rare condition, thought to be a hamartoma in which cells of the pilosebaceous unit fail to develop appropriately. Although it is usually an isolated phenomenon, it has been associated with other defects, including those of the skeletal, ocular and central nervous system. A girl with this condit...

journal_title：Clinical and experimental dermatology

authors： Woods KA,Larcher VF,Harper JI

更新日期：1994-03-01 00:00:00

abstract：:Contact hypersensitivity from topical corticosteroids is becoming increasingly recognized; it is present in 2-5% of the patients attending contact dermatitis clinics. The use of a corticosteroid series containing tixocortal pivalate 1% (petrolatum), to detect hypersensitivity to hydrocortisone, and other steroids 1% (...

journal_title：Clinical and experimental dermatology

authors： Wilkinson SM

更新日期：1994-01-01 00:00:00

abstract：:Dermatofibromata are common benign dermal tumours of unknown aetiology. They usually present as a single lesion on the limbs of young adults. Multiple dermatofibromata have been reported occurring in patients with autoimmune disease, who were receiving immunosuppressive treatment. A 25-year-old female is reported who ...

journal_title：Clinical and experimental dermatology

authors： Stainforth J,Goodfield MJ

更新日期：1994-01-01 00:00:00

abstract：:Cutaneous drug eruptions have a variety of clinical features. Lichenoid drug eruptions are rare and may be difficult to diagnose. A case of a simvastatin-induced lichenoid eruption with skin and mucosal involvement is reported. ...

journal_title：Clinical and experimental dermatology

authors： Roger D,Rolle F,Labrousse F,Brosset A,Bonnetblanc JM

更新日期：1994-01-01 00:00:00

abstract：:Eleven cases of cutaneous B-cell lymphoma (CBCL) were studied. The ages at presentation ranged from 34 to 79 years (mean = 59.9 years). Six patients were female and five male. Five of the 11 patients had a solitary tumour and the other six had multiple tumours at initial presentation. According to Burg's classificatio...

journal_title：Clinical and experimental dermatology

authors： Nagatani T,Miyazawa M,Matsuzaki T,Hayakawa H,Iemoto G,Kim ST,Baba N,Aihara M,Miyamoto H,Nakajima H

更新日期：1993-11-01 00:00:00

abstract：:Clinicians have become increasingly aware of the important effects of psoriasis on patients' quality of life. As a result, several measures of the disabilities and handicaps associated with psoriasis have been developed. The Psoriasis Disability Index (PDI) has been shown to be sensitive to changes in the extent of le...

journal_title：Clinical and experimental dermatology

authors： Kent G,al-Abadie M

更新日期：1993-09-01 00:00:00

abstract：:A patient with primary malignant melanoma localized to the right gluteal region is described. Four years later and after intercurrent influenza, disseminated metastases of malignant melanoma to the skin occurred. After a further 6 months melanodermia developed and lasted until the death of the patient (6 months later)...

journal_title：Clinical and experimental dermatology

authors： Péc J,Plank L,Mináriková E,Palencárová E,Rollová Y,Lazárová Z,Auxtová S,Lauko L

更新日期：1993-09-01 00:00:00